Contract Details
Title

Silk Mill Gardens - Demolition United Kingdom

Country
Language
English
Organization
Published Date
09.03.2024
Awarded Date
09.03.2020
Overview
Contract Award's Details : Silk Mill Gardens - Demolition Leeds City Council Investigation of bacterial involvement in canine CRGV cases Canine cutaneous and renal glomerular vasculopathy (CRGV and sometimes known as & 039;Alabama rot& 039;) in the UK first appeared in 2012, with 4 cases presenting to a Anderson Moores from practices around the New Forest, Hampshire with acute kidney injury (AKI) and skin lesions. The numbers of cases and geographical distribution of the disease have in the main increased year on year, with 190 cases now reported. The disease is normally characterised by the initial appearance of skin lesions on the limbs +/- face and body. Some dogs then go on to develop acute deterioration of kidney function and death. On post mortem blood vessels are seen to be blocked by thrombi (clots). The cause of the disease is unknown, despite investigation. Tests undertaken include investigation for E.coli (given some similarities to human haemolytic uremic syndrome), Circovirus, pan viral metagenomics and bacterial 16S probes, heavy metals and ethylene glycol poisoning. Leptospira has been investigated as a cause, and although presence of this organism was high in cases, results couldn& 039;t indicate a causative link. Despite the extensive investigations already undertaken, a few bacterial causes remain possible based upon experimental results or pathological findings. Toxigenic bacteria have not been found in the kidneys, but this does not rule out their presence in the skin lesions, with local production of toxins into the circulation causing subsequent kidney injury. Shiga toxigenic E. coli were hypothesised to cause similar disease in the USA with kidney injury. Aeromonas hydrophilia causes similar skin lesions in fish and amphibians with subsequent kidney failure, as well as disease in humans, and are also toxigenic, with toxin production in limbs causing organ injury. Leptospira were unusually prevalent in cases and can cause kidney injury. Without an analysis of cases vs healthy animals it is impossible to confirm the likely association of these bacteria (Aeromonas, E.coli and Leptospira Please note that Defra procurement uses an E-tendering system for Procurement activities. This is currently provided by Bravo Solutions. To access appropriate tendering and contractual documents, please access the E-Tendering portal at https://defra.bravosolution.co.uk", ensuring that your registration includes "Defra". If you have any problems with this system, please contact Bravo on their telephone helpline number 0800 368 4850 or by emailing them at help@bravosolution.co.uk. " E-Tendering portal help United Kingdom Contract value : 16,950.00 GBP Contractors : Demolition Services Limited See in details 10/03/2020 31/03/2020 76165642 20/04/2020 Defra Network eTendering Portal Address : 17 Nobel House SW1P 3JR, London Ajay Tyagi Ajay.Tyagi@defra.gov.uk 00 United Kingdom United Kingdom Contract Awards United Kingdom ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe-354841-tender_229808-851179 See in details 31/03/2020 25,000.00 GBP
NAICS
Power Specialized Freight (except Used Goods) Trucking Investigation General Freight Trucking Metal Can
CPVS
Toxins Goods vessels Probes System, storage and content management software package Fish, crustaceans and aquatic products Mains Networks Networking, Internet and intranet software development services Demolition, site preparation and clearance work Fish Small animals Feasibility study, advisory service, analysis Blocks System, storage and content management software development services Networking, Internet and intranet software package Other services Posts Ethylene glycol Demolition work
UNSPSC
-
Regions
Europe Northern Europe
Sectors
Building Environment and Pollution-Recycling Automobiles and Auto Parts Non-Renewable Energy Supply Solar Photovoltaic PV Energy Postal and Courier Services Roads and Highways-Bridge Oil and Gas Infrastructure Printing and Publishing Services Metals and Non-Metals Construction Energy-Power and Electrical Computer Hardwares and Consumables Industry Building Material Marine
Contractor
Contract Value
25,000.00 GBP
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