PANMRA-24-P-0000_005879 AI for Infectious Disease Threats Description THIS IS A NOITICE OF INTENT TO AWARD A SOLE-SOURCE CONTRACT AND IS NOT A REQUEST FOR COMPETITIVE PROPSALS. The Experimental Therapeutics (ET) Branch would like to establish an Indefinite Delivery Indefinite Quantity (IDIQ) contract for Artificial Intelligence (AI) Machine-Learning (ML) in silico screening of candidate drug compounds against known targets of infectious disease threats of interest. In their own facilities, the contractor will screen multimillions of approved and novel compounds against multiple targets to be identified by the Government to identify and develop drug-like ligands. The contractor will utilize ML decision tree algorithms for potent compound identification followed by evaluation of potential toxicity, off-target effects and potential structure based metabolic liabilities. DEPT OF DEFENSE | DEFENSE HEALTH AGENCY (DHA) 808 SCHREIDER ST, FORT DETRICK , MD 21702, USA Primary Point of Contact: Ryan Jorgensen, ryan.r.jorgensen.civ@health.mil, Phone Number 3016192359 Secondary Point of Contact: TONYA KREPS, tonya.r.kreps.civ@health.mil, Phone Number 3016192519 linda.t.hinson.civ@health.mil Tender Notice International Competitive Bidding PANMRA-24-P-0000_005879 United States of America GT-108155204